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Our top choices for Downtown Clayton hotels

1. Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended StayDowntown Clayton
8.8 out of 10, Excellent, (3,530 reviews)
The price is CA $148
CA $172 total
includes taxes & fees
Dec 6 - Dec 7

2. AC Hotel St. Louis Clayton
AC Hotel St. Louis ClaytonDowntown Clayton
9.2 out of 10, Wonderful, (426 reviews)
The price is CA $181
CA $212 total
includes taxes & fees
Nov 15 - Nov 16

3. Le Méridien St. Louis Clayton
Le Méridien St. Louis ClaytonDowntown Clayton
8.8 out of 10, Excellent, (802 reviews)
The price is CA $215
CA $253 total
includes taxes & fees
Nov 22 - Nov 23

4. Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Seven Gables, St. Louis West, a Tribute Portfolio HotelDowntown Clayton
8.4 out of 10, Very good, (603 reviews)
The price is CA $211
CA $259 total
includes taxes & fees
Nov 15 - Nov 16

5. The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. LouisDowntown Clayton
9.2 out of 10, Wonderful, (588 reviews)
The price is CA $776
CA $905 total
includes taxes & fees
Nov 27 - Nov 28

6. Drury Plaza Hotel St. Louis Brentwood
Drury Plaza Hotel St. Louis Brentwood2.5 km from Downtown Clayton
9.6 out of 10, Exceptional, (1,011 reviews)
The price is CA $181
CA $215 total
includes taxes & fees
Nov 22 - Nov 23

7. Courtyard by Marriott St. Louis Brentwood
Courtyard by Marriott St. Louis Brentwood2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (914 reviews)
The price is CA $167
CA $204 total
includes taxes & fees
Nov 15 - Nov 16

8. The Knight Center at Washington University
The Knight Center at Washington University2.2 km from Downtown Clayton
9.4 out of 10, Exceptional, (723 reviews)
The price is CA $189
CA $217 total
includes taxes & fees
Nov 22 - Nov 23

9. Moonrise Hotel
Moonrise Hotel3.4 km from Downtown Clayton
9.0 out of 10, Wonderful, (2,057 reviews)
The price is CA $214
CA $254 total
includes taxes & fees
Dec 1 - Dec 2

10. The Cheshire
The Cheshire3.1 km from Downtown Clayton
8.8 out of 10, Excellent, (1,006 reviews)
The price is CA $211
CA $250 total
includes taxes & fees
Nov 29 - Nov 30

11. Hampton Inn & Suites St. Louis at Forest Park
Hampton Inn & Suites St. Louis at Forest ParkDogtown, 5.3 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,002 reviews)
The price is CA $184
CA $217 total
includes taxes & fees
Nov 15 - Nov 16

12. Hilton Garden Inn St. Louis Airport
Hilton Garden Inn St. Louis Airport8.3 km from Downtown Clayton
8.4 out of 10, Very good, (1,003 reviews)
The price is CA $143
CA $167 total
includes taxes & fees
Nov 14 - Nov 15

13. The West End
The West EndCentral West End, 7.7 km from Downtown Clayton
8.6 out of 10, Excellent, (709 reviews)
The price is CA $99
CA $144 total
includes taxes & fees
Nov 10 - Nov 11

14. Hyatt Select St. Louis Airport
Hyatt Select St. Louis Airport9.7 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,020 reviews)
The price is CA $155
CA $192 total
includes taxes & fees
Nov 11 - Nov 12

15. The Royal Sonesta Chase Park Plaza St. Louis
The Royal Sonesta Chase Park Plaza St. LouisCentral West End, 6.3 km from Downtown Clayton
9.2 out of 10, Wonderful, (1,007 reviews)
The price is CA $211
CA $290 total
includes taxes & fees
Nov 22 - Nov 23

16. Drury Inn & Suites St. Louis Forest Park
Drury Inn & Suites St. Louis Forest Park5.5 km from Downtown Clayton
9.4 out of 10, Exceptional, (1,032 reviews)
The price is CA $191
CA $223 total
includes taxes & fees
Nov 15 - Nov 16

17. Pear Tree Inn St. Louis Airport
Pear Tree Inn St. Louis Airport10.4 km from Downtown Clayton
9.4 out of 10, Exceptional, (3,366 reviews)
The price is CA $127
CA $151 total
includes taxes & fees
Nov 15 - Nov 16

18. Forest Park Hotel by MDR
Forest Park Hotel by MDRThe Hill, 5.6 km from Downtown Clayton
7.4 out of 10, Good, (1,708 reviews)
The price is CA $103
CA $127 total
includes taxes & fees
Dec 9 - Dec 10

19. La Quinta Inn & Suites by Wyndham St Louis Route 66
La Quinta Inn & Suites by Wyndham St Louis Route 6611.9 km from Downtown Clayton
8.4 out of 10, Very good, (1,006 reviews)
The price is CA $133
CA $155 total
includes taxes & fees
Dec 10 - Dec 11

20. Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The ArchDowntown St. Louis, 13.2 km from Downtown Clayton
8.6 out of 10, Excellent, (4,400 reviews)
The price is CA $159
CA $187 total
includes taxes & fees
Nov 27 - Nov 28
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Downtown Clayton
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() AC Hotel St. Louis Clayton | 9.2 Wonderful 426 reviews | View | ||||||
![]() The Ritz-Carlton, St. Louis | 9.2 Wonderful 588 reviews | View | ||||||
![]() Clayton Plaza Hotel & Extended Stay | 8.8 Excellent 3,530 reviews | View | ||||||
![]() Le Méridien St. Louis Clayton | 8.8 Excellent 802 reviews | View | ||||||
![]() Seven Gables, St. Louis West, a Tribute Portfolio Hotel | 8.4 Very good 603 reviews | View |
Where to stay in Downtown Clayton
Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.

Downtown St. Louis
Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

Clayton
Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

St. Charles Historic District
Discover a national historic district featuring over 100 buildings, including the First Missouri State Capitol and St. Charles Odd Fellows Hall, showcasing architectural styles like Greek Revival and Italianate.

Central West End
Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Creve Coeur
Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.






































































































